Qiyu Liang

This study engineers the Arabidopsis FLS2 receptor to control its oligomerization, showing that dimerization enhances immune responses while tetramerization impairs receptor turnover and weakens sustained signaling.

The paper analyzes phase-separating proteins across 1,106 species to reconstruct the evolutionary history of protein condensation and identifies phase separation-regulated signaling hubs.

MolPhase predicts protein phase separation using physicochemical features and experimental data, showing T3Es undergo homotypic phase separation in vitro and in vivo.