Author

Shengpan Zhang

University of OxfordORCID 0000-0002-1134-7101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Erdinc SezginiD· 2 shared Quentin James SattentauiD· 2 shared Adrien SchahliD· 1 shared Ellen SjuleiD· 1 shared Franziska RagalleriD· 1 shared Helen RobertsoniD· 1 shared Jose Cabezas-CaballeroiD· 1 shared Lachlan Paul DeimeliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Erdinc SezginORCID

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2 papers

Recent·Most cited

BiophysicsAdvanced SciencePeer-reviewedFeb 24, 2026

Lipid-facilitated opening of the ADAM10 sheddase revealed by enhanced sampling simulations

Adrien Schahl, Nandan Haloi, Marta Carroni…·Rebecca J. Howard

This study uses simulations to show that phosphatidylserine induces conformational changes in ADAM10, leading to its activation and reduced antibody binding.

3 citationstop 2%

biophysical modelingprotein folding & dynamics

𝕏 PostBluesky

Cell BiologyNature CommunicationsPeer-reviewedJan 15, 2024

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis

Linnea Z. Drexhage, Shengpan Zhang, Maeva Dupont…·Quentin James Sattentau

The paper shows that ADAM10-mediated removal of mucins during T cell apoptosis enhances macrophage efferocytosis.

30 citationstop 4%

humanproteomics

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