Alessandro De Simone

The paper identifies a moving front of osteoblast maturation that controls proliferation during zebrafish scale regeneration, explaining size scaling through regulated cell dynamics.

The paper quantifies Erk signaling gradients in zebrafish fin regeneration and shows they scale with tissue amputation size to control skeletal regeneration.

The paper shows Erk signaling waves in zebrafish scale regeneration induce inhibitor transcript waves and modulate osterix transcription, linking wave dynamics to tissue growth and maturation.

This study introduces 3D culture systems to model human somitogenesis, revealing the role of the segmentation clock in establishing somite compartments.

The paper develops a reaction-diffusion model to explain Erk activity waves in zebrafish scale regeneration, showing how feedback loops control wave properties and propagation.

The paper shows that PIP2 forms dynamic cortical structures in C. elegans embryos, regulating actin organization and cell polarity during asymmetric division.