Author

Iva Staniczková Zambo

Masaryk UniversityORCID 0000-0002-1189-0702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Jakub NeradiliD· 2 shared Jan SkodaiD· 2 shared Dušan ZoufalýiD· 1 shared Jaroslav ŠtěrbaiD· 1 shared Kristýna PoláškováiD· 1 shared Lucie CurylovaiD· 1 shared Michal KýriD· 1 shared Michal MahdaliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Jakub NeradilORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 6, 2026

Receptor tyrosine kinase inhibitors trametinib and axitinib effectively target the neoplastic component of giant cell tumor of bone in vitro

Veronika Knechtova, Michal Mahdal, Iva Staniczková Zambo…·Jakub Neradil

This study identifies trametinib and axitinib as effective inhibitors of GCTB stromal cells in vitro, showing selective activity against tumor cells compared to healthy controls.

DOI 10.64898/2026.10.06.756991

humanexperimental assay

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Cancer BiologyCellular OncologyPeer-reviewedDec 1, 2024

Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

Lucie Curylova, Iva Staniczková Zambo, Jakub Neradil…·Jan Skoda

This study shows that restoring p53 activity can target aggressive pediatric sarcomas with stem-like traits by inducing apoptosis in cancer cells while sparing healthy cells.

1 citation

mousehuman

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