Gregory S. Yochum

This study shows autophagy prevents ER stress-induced tight junction barrier disruption by maintaining claudin-2 homeostasis and occludin localization.

The paper identifies region-specific host-microbiome associations in the human intestine using transcriptomic and microbiome data from non-inflamed tissue.

The paper develops a high-throughput platform to identify gut microbial accessible carbohydrates (MACs) using engineered Bacteroides thetaiotaomicron strains, enabling prebiotic development.

This study shows that loss of STIM2 in colorectal cancer promotes tumor growth and metastasis through metabolic reprogramming and activation of the PERK-ATF4 ER stress pathway.

This study shows that MUC5B levels are reduced in ulcerative colitis colonic tissues and organoids, and IL-1β fails to induce MUC5B expression in UC-derived organoids.