Author
Xin Chen
University of Illinois Urbana-ChampaignORCID 0000-0002-1224-0285Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2023-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 40 mutual co-author links4 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
TRIM21 is a molecular rheostat for influenza A virus replication
Qi Wen Teo, Huibin Lv, Tossapol Pholcharee…·Nicholas C. Wu
This study shows TRIM21 acts as a molecular rheostat regulating influenza A virus replication by modulating ubiquitination and innate immune signaling, with PRKDC as a compensatory antiviral factor when TRIM21 is absent.
DOI 10.64898/2026.03.16.711963 - ImmunologyCell Host & MicrobePeer-reviewed
Evolution of antibody cross-reactivity to influenza H5N1 neuraminidase from an N2-specific germline
Huibin Lv, Yang Wei Huan, Qi Wen Teo…·Nicholas C. Wu
This study identifies an antibody that cross-reacts with H5N1 and H3N2 neuraminidases and shows how somatic hypermutation enables this cross-reactivity.
3 citations - ImmunologybioRxivPreprint
An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies
Yiquan Wang, Huibin Lv, Ruipeng Lei…·Nicholas C. Wu
This study curates a dataset of influenza HA antibodies and develops an explainable language model to predict antibody specificity, identifying and validating HA stem antibodies.
DOI 10.1101/2023.09.11.557288