Author

Osamu Takeuchi

Kyoto UniversityORCID 0000-0002-1260-6232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Yasuhiro MurakawaiD· 2 shared Ai Kanemaru· 1 shared Akifumi Takaori‐KondoiD· 1 shared Akira FukaoiD· 1 shared Alexis VandenboniD· 1 shared Fabian HiaiD· 1 shared Haruna TakedaiD· 1 shared Hideya KawajiiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenomics

Yasuhiro MurakawaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 8, 2025

Regnase-1 Promotes Tumor-Initiating Activity in Non-Small Cell Lung Cancer

Keito Okazaki, Madoka Kawaguchi, Shohei Murakami…·Hozumi Motohashi

This study shows Regnase-1 promotes tumor-initiating activity in NSCLC by suppressing the SOX2 pathway, and its inhibition reduces tumor growth and enhances anti-cancer immunity.

DOI 10.1101/2025.07.08.663650

humanbulk RNA-seq

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GenomicsbioRxivPreprintJul 3, 2019

Dynamics and Topology of Human Transcribed Cis-regulatory Elements

Shigeki Hirabayashi, Shruti Bhagat, Yu Matsuki…·Yasuhiro Murakawa

The paper develops NET-CAGE to detect nascent RNA 5-ends, identifies enhancer-promoter pairs, and reveals topological connections of cis-regulatory elements across cell types.

DOI 10.1101/689968

humanmouse

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Molecular BiologybioRxivPreprintApr 4, 2019

Codon Bias Confers Stability to mRNAs via ILF2 in Humans

Fabian Hia, Sheng Fan Yang, Yuichi Shichino…·Osamu Takeuchi

The paper shows that codon bias affects mRNA stability in humans through ILF2, with GC3 codons stabilizing and AT3 codons destabilizing mRNA.

2 citations

humanbulk RNA-seq

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