Author
Ghent UniversityORCID 0000-0002-1286-4485Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Joachim Tetteh Siaw, Arne Claeys, Wei‐Yun Lai…·Jimmy Van den Eynden
This study identifies RUVBL1 and RUVBL2 as druggable regulators of MYCN in neuroblastoma, showing their inhibition reduces MYC signaling and induces cell cycle arrest and apoptosis.
Katarzyna Radke, Kristina E. Aaltonen, Erick Andrés Muciño-Olmos…·Daniel Bexell
This study repurposes statins and phenothiazines to treat chemoresistant neuroblastoma, showing synergistic effects and improved survival in preclinical models.
Joachim T. Siaw, Peter Merseburger, Marcus Borenäs…·Jimmy Van den Eynden
The paper uses spatial transcriptomics to analyze neuroblastoma microenvironments, identifying novel paracrine interactions between cancer cells and surrounding cells.
Jonatan L. Gabre, Peter Merseburger, Arne Claeys…·Jimmy Van den Eynden
The paper introduces CLEAN, a web tool for exploring neuroblastoma data, focusing on DNA damage response to identify drug targets.
Tom Luijts, Kerryn Elliott, Joachim T. Siaw…·Jimmy Van den Eynden
The paper uses post-mortem tissues to study mutational clonality in healthy tissues, finding smoking-induced clonal changes in oral epithelia and confirming NOTCH1/2-, TP53-, and FAT1-driven clones.