Thomas G. Martin

This study investigates cardiac myofibril remodeling in Burmese pythons during digestion using multi-omics approaches, revealing post-translational modifications as key to increased contractility.

The paper identifies a conserved postprandial metabolite, pTOS, that links nutrient intake to energy balance through a gut-brain pathway in pythons and mice, with potential relevance to humans.

This study compares the progression of skeletal muscle atrophy caused by fasting and disuse across different muscle fiber types using transcriptomic analysis.

The paper assembles and annotates the first whole genome of the ball python (Python regius), providing a high-quality resource for studying snake-specific traits and physiological adaptations.

This study shows that Burmese pythons can sustain cardiac growth through cardiomyocyte hyperplasia by re-entering the cell cycle after frequent feeding.

The paper identifies CaMKIIδ-B subcellular localization as a determinant of myocardial recovery in heart failure, showing cytoplasmic retention impairs recovery.

This study identifies FoxO1-dependent autophagy as a conserved mechanism for regression of physiological cardiac hypertrophy across species.

This paper introduces a DLP-based 3D printing method for rapid, high-efficiency fabrication of human engineered heart tissues to model cardiac disease.