Author

Tim Casper Passchier

University of LeedsORCID 0000-0002-1306-5853Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Chris H. HilliD· 1 shared Cy Michael JeffriesiD· 1 shared Daniel P. MaskelliD· 1 shared David J. FilmaniD· 1 shared David J. RowlandsiD· 1 shared Eero V. HietaneniD· 1 shared H KungiD· 1 shared Ian BrierleyiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMolecular Biology

Chris H. HillORCID

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3 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedAug 21, 2026

A protein-dependent riboswitch activates ribosomal frameshifting in cardioviruses

Jemma K. Betts, Cy Michael Jeffries, Tim Casper Passchier…·Chris H. Hill

The paper investigates how the 2A protein interacts with the RNA genome of cardioviruses to activate ribosomal frameshifting through structural changes in the RNA.

2 citations

experimental assay

𝕏 PostBluesky

MicrobiologyPLoS PathogensPeer-reviewedSep 19, 2024

Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.

Natalie J. Kingston, Joseph S. Snowden, Keith Grehan…·Nicola J. Stonehouse

The paper determines the molecular mechanism of VP0 cleavage in enteroviruses using structural and bioinformatic analysis of a provirion intermediate.

13 citations

structural biologybiophysical modeling

𝕏 PostBluesky

MicrobiologyScientific ReportsPeer-reviewedJun 18, 2024

The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures

Tim Casper Passchier, Joshua B. R. White, Daniel P. Maskell…·John N. Barr

The paper reports the cryoEM structure of Hendra henipavirus nucleoprotein bound to RNA, revealing unique interactions in its multimeric assembly and insights into paramyxoviral nucleocapsid architecture.

4 citations

viruscryo-EM

𝕏 PostBluesky