Daniela Sofia Valdes

The paper introduces MEMBRYO, a method for continuous SILAC proteomics in live embryos, revealing post-transcriptional regulation during neurogenesis.

The paper introduces openDVP, a framework for deep visual proteomics, demonstrating its application in three tissue studies to integrate spatial single-cell phenotypes with proteomic data.

This study shows maternal smoking disrupts placental function by altering syncytiotrophoblast and macrophage biology, leading to fetal growth restriction.

The paper develops methods to collect intestinal interstitial fluid from different segments and shows segment-specific differences in microbiota-derived metabolites, cytokines, and proteins compared to plasma and serum.

The paper identifies a disrupted trophoblast transition in preeclampsia, linking placental pathology to maternal syndrome through multi-omics profiling and in vitro analyses.