Nicola Romanò

This meta-analysis examines whether the duration of chronic restraint stress affects behavioral test outcomes in rats, finding no correlation between duration and effect sizes.

The paper quantifies Ca2+ responses in rat corticotrophs to CRH and AVP, showing AVP elicits stronger and faster responses while CRH modulates input integration.

This study reviews CVS procedures and finds that only one of 385 studies used a biologically meaningful effect size to determine sample size, suggesting poor adherence to the Reduction principle of the Three Rs.

This study examines how variations in chronic variable stress procedures affect behavioral outcomes in mice, finding that longer and more diverse stress regimens reduce effect sizes in certain tests.

This study investigates transcriptional heterogeneity in corticotrophs using scRNA-seq, finding that they transition between transcriptional states rather than existing as fixed subpopulations.

This paper introduces an iCRISPRa system to activate transcription factors in iPSCs, identifying IGFBP2 as critical for hematopoietic progenitor production.

The paper identifies IGFBP2 as a key factor secreted by arterial cells that enhances hematopoietic progenitor development in vitro.

The paper identifies markers of naive and lineage-primed hematopoietic progenitors from hPSCs using single-cell RNA sequencing and functional assays.