Author

Henry S. Pan

University of California, San FranciscoORCID 0000-0002-1323-037XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Hyunil JoiD· 2 shared William F. DeGradoiD· 2 shared Alissa L. NanaiD· 1 shared Anthony YungiD· 1 shared Argentina Lario LagoiD· 1 shared Arthur A MeloiD· 1 shared Athena Quddus· 1 shared Carlo CondelloiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Hyunil JoORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 15, 2026

Distinct tau filament folds in familial frontotemporal dementia due to the MAPT S305I mutation

Henry S. Pan, Gregory E. Merz, Alissa L. Nana…·Daniel R. Southworth

This study identifies distinct tau filament structures in FTLD-tau caused by the MAPT S305I mutation, revealing a unique 4-layer architecture and potential RNA-like polyanion binding.

2 citations

humanexperimental assay

𝕏 PostBluesky

BiophysicsChemical SciencePeer-reviewedJan 1, 2024

De novo Design of Peptides that Bind Specific Conformers of α-Synuclein

Hailey M. Wallace, Hyunjun Yang, Sophia K. Tan…·William F. DeGrado

This paper introduces a computational method to design peptides that bind specific conformers of α-synuclein fibrils, resulting in a peptide that slows amyloid formation and shows high specificity.

9 citations

proteomicsdeep learning

𝕏 PostBluesky