Ailin Lepletier

The paper shows that sub-clinical exposure to Streptococcus pyogenes generates functional immune responses and contributes to immunity by adulthood.

This study investigates low-dose interleukin 2 (LD-IL-2) as an immunotherapeutic intervention in a rat model of acute rheumatic fever, showing reduced cardiac inflammation and increased regulatory T-cells.

This study shows that IL-17 deficiency in mice leads to increased S. pyogenes dissemination after respiratory infection, contributing to invasive streptococcal disease.

This study integrates proteomic and transcriptomic data from human T-cells to show time-dependent metabolic reprogramming and divergence in gene expression during activation.