José Maria Moreira Dias

The paper challenges the traditional view that morphogen concentration fluctuations determine transition zone width, showing instead that cellular readout noise is the key factor.

This study tracks DNA-origami nanostructures in zebrafish embryos using imaging and single-cell RNA sequencing to understand their biodistribution and clearance mechanisms.

The paper identifies a Shh/Gli-driven three-node timer motif that controls the sequential generation of motor neurons and serotonergic neurons in the brainstem.