Madhan Mohan Chandra Sekhar Jaggarapu

The paper develops two strategies to increase mesaconate levels in the gut to reduce inflammation in Crohn's Disease mouse models.

This paper develops a polymer, 1,6 MMA, that suppresses inflammation by reducing IL-2 and increasing mitochondrial ROS in T cells, showing therapeutic potential in collagen-induced arthritis.

This study shows that reducing antigen exposure exponentially decreases pro-inflammatory T cell responses and promotes regulatory T cells in a mouse model of rheumatoid arthritis.