Dhiraj Devidas Bhatia

This paper compares hydrothermal and microwave-assisted synthesis of carbon quantum dots from bearberry extract, showing how synthesis method affects surface chemistry, photophysical properties, and biological activity.

This study investigates how hypoxia affects DNA nanocage uptake in cells and zebrafish, finding that surface charge engineering can improve delivery under hypoxic conditions.

This paper develops a DNA hydrogel that rapidly stops bleeding and promotes tissue regeneration in mice by combining hemostasis with bioactive properties.

This study uses DNA nanocages to deliver Levodopa in a zebrafish Parkinson's model, improving neuroprotection and reversing disease symptoms.

This study synthesizes and evaluates triazole-pyrazine derivatives for anti-HSV-1 and antioxidant activity, finding compounds 5f and 5t show improved antiviral efficacy compared to Acyclovir.

This paper develops an impedimetric aptasensor using DNA tetrahedral nanostructures for ultrasensitive IL-6 detection with a limit of detection of 55 ag/mL.

This paper develops a portable, smartphone-compatible electrochemical sensor for serotonin detection in serum, demonstrating high sensitivity, selectivity, and reliability in clinical samples.

This study shows enzyme activity enhances ligand diffusion and receptor-mediated endocytosis by generating mechanical fluctuations in the extracellular matrix.

This paper synthesizes red-emitting carbon quantum dots from Hamelia patens and evaluates their antioxidant activity, cytotoxicity, and bioimaging potential.

This study develops Curcumin-Magnesium DNA hydrogels that show concentration-dependent swelling and induce oxidative stress-mediated apoptosis in cancer cells.

This paper develops an electrochemical aptasensor for ultrasensitive detection of IL-6 in clinical biofluids, showing high sensitivity and biocompatibility for septic cardiomyopathy diagnostics.

This study evaluates how physicochemical factors affect the stability of DNA tetrahedral nanostructures in vitro.

This paper develops nitrogen-doped carbon dots from chamomile extract using solvothermal synthesis, showing high fluorescence quantum yield and biocompatibility for bioimaging.

The paper shows that increased cell surface sialylation enhances DNA nanocage uptake by remodeling the membrane and recruiting caveolae-mediated endocytosis in RPE1 cells.

This paper develops DNA-based hydrogels with tunable mechanical properties to regulate cellular behavior and cytoskeleton reorganization in RPE1 cells.

This study identifies miR-1307-5p in salivary extracellular vesicles as a biomarker of chemoresistance in oral squamous cell carcinoma and shows its inhibition restores cisplatin sensitivity.

This paper develops a DNA tetrahedron conjugated with alpha-tocopherol to enhance cellular uptake and selectively kill cancer cells through ROS-induced apoptosis.

This paper demonstrates DNA nanocages (TDNs) for targeted delivery of biomolecules into Arabidopsis pollen tubes, modulating growth through actin reorganization and ROS modulation.

This paper demonstrates that DNA nanocages delivering aspirin reduce excitotoxicity and promote neuroprotection in zebrafish models of ischemic stroke.

This paper develops a DNA-silk fibroin hybrid hydrogel that enhances mesenchymal stem cell differentiation and accelerates wound healing in mice.

This paper describes a protocol for synthesizing fluorescent carbon quantum dots from mango leaves and evaluates their biocompatibility and cellular uptake for biological applications.

This paper describes the synthesis of green-emitting carbon quantum dots and evaluates their biocompatibility and cellular uptake in mouse and zebrafish models.

This paper evaluates siIL-1β-anti-CD44-Liposomes as an anti-inflammatory therapy, showing reduced pro-inflammatory cytokines and increased anti-inflammatory cytokines in macrophages.

This study uses MD simulations to investigate how cationic lipids interact with DNA nanocages to enhance drug delivery efficiency.

This paper introduces a PDMS-based microwell device for generating uniform-sized cancer spheroids, enhancing 3D cancer modeling and drug testing.

This study shows that functionalizing DNA nanodevices with growth-factor ligands improves their cellular and in vivo uptake and effectiveness.

This study develops a pH-responsive nanocomposite for curcumin delivery, showing 31% loading and 85% encapsulation efficiency with controlled release and anti-cancer activity against MCF-7 cells.

This study synthesizes fluorescent carbon dots (CDs) and demonstrates their ability to selectively distinguish cancer cells from epithelial cells based on higher uptake and fluorescence intensity.

This study investigates the aggregation of branched chain amino acids (BCAAs) in Maple syrup urine disease (MSUD) and finds they form amyloid-like fibrils with cytotoxic effects.

This study investigates DNA nanocages loaded with neurotransmitters as a therapeutic approach to clear α-synuclein aggregates in Parkinson's disease models in cells and zebrafish.