Kunio Hirata

This study determines the crystal structure of a pufferfish umami taste receptor ortholog, revealing how it binds both L- and D-amino acids through structural adaptations.

This study uses cell-free protein crystallization to determine atomic structures of saccharides bound to galectin-10, revealing binding modes not accessible by conventional methods.

This paper develops a cell-free protein crystallization method to determine the structure of an intrinsically disordered protein and identifies key residues stabilizing its helical conformation.

This paper demonstrates the use of intensity-based hierarchical clustering to detect structural polymorphs in diffraction datasets from multiple crystals.

The paper reports X-ray structures of the human ETB receptor bound to agonists, revealing molecular mechanisms of activation and partial agonism.