BioengineeringAdvanced SciencePeer-reviewed
Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells
Hyeon Ryoo, Regina Giovanni, Hannah Kimmel…·Gregory H. Underhill
This study uses stiffness-variable ECM microgels to screen and culture primary human hepatic stellate cells in 3D, showing that heterogeneous microenvironments reduce matrix remodeling and metabolic activity compared to homogeneous ones.
8 citations