Agnès Thierry

The paper investigates the 3D genome structuration and dynamics of bacteriophage PAK_P3 during infection of Pseudomonas aeruginosa, revealing specific interactions between phage and host genomes.

This study investigates the role of HU in chromosome organization and replication in Streptococcus pneumoniae, showing it promotes long-range interactions and supports replication and segregation.

The paper shows that Z-DNA formation promotes totipotent-like state and primes Zscan4-dependent chromatin compartmentalization during early mouse development.

This paper investigates the mechanism of homology search expansion during DNA break repair, revealing how chromatin structure, NPF stiffening, and resection drive genome-wide search.

The paper shows that viral proteins activate PARIS-mediated tRNA degradation, and viral tRNAs rescue infection by preventing cleavage.

This study presents a chromosome-level genome assembly for the European Green Woodpecker, Picus viridis, using short and long-read sequencing combined with Hi-C scaffolding.

The paper shows that sister chromatid cohesion inhibits cohesin-mediated DNA loop expansion during G2 phase.

The paper identifies how the 2μ plasmid in yeast binds to inactive chromosomal regions through nucleosome signals and RNA Pol II depletion, revealing a stable and rapid tethering mechanism.

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

The paper investigates whether neuroinvasion and anosmia are independent outcomes of SARS-CoV-2 infection by analyzing clinical, olfactory, and neuroinflammatory responses in infected golden hamsters.

This study shows that bacterial chromosomes can undergo chromatin assembly, activity, looping, and compartmentalization in yeast, driven by their sequence composition.

The paper presents chromosome-scale genome assemblies of Acanthamoeba castellanii and shows infection-induced chromatin reorganization during Legionella pneumophila infection.

The paper tests if the 601 DNA sequence can position nucleosomes in vivo in yeast, finding that it does not reliably do so in a tandem repeat array context.

This study shows cohesin promotes cis dsDNA over-sampling during homology search in yeast by blocking cohesin progression and enabling loop expansion-coupled scanning.

This study shows that FACT is required for cohesin stability on chromatin and the formation of cohesin-dependent TAD-like structures, but not sister chromatid cohesion.

The paper identifies Eco1's role in negatively regulating cohesin translocase activity during yeast mitosis, affecting DNA loop extrusion and chromosome folding.

The paper redesigns a genomic region for improved Hi-C analysis, revealing insights into homolog pairing and loop formation during meiosis.

The paper uses Hi-C to analyze chromosome structure dynamics in budding yeast during the cell cycle, revealing SMC-dependent structural transitions and mitotic reorganization.