Thomas Metzler

This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.

This study identifies ROR2 as a regulator of cellular plasticity in pancreatic neoplasia, showing it promotes an aggressive PDAC phenotype and resistance to KRAS inhibitors.

The paper investigates how NREM sleep spindles affect emotion regulation and memory consolidation in PTSD after stress exposure, finding increased spindles correlate with reduced anxiety but poorer memory recall.