Author

Adam Sorbie

LMU KlinikumORCID 0000-0002-3330-4612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Dirk HalleriD· 2 shared Katja SteigeriD· 2 shared Miriam von Stern· 2 shared Olivia I. ColemaniD· 2 shared Alessandra RivaiD· 1 shared Amira MetwalyiD· 1 shared Andreas DunkeliD· 1 shared Barbara U. SchramliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Dirk HallerORCID

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2 papers

Recent·Most cited

Cancer BiologyNature MetabolismPeer-reviewedSep 1, 2025

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

Olivia I. Coleman, Adam Sorbie, Alessandra Riva…·Dirk Haller

This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.

16 citationstop 5%

mousehuman

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Cancer BiologyJournal of Crohn s and ColitisPeer-reviewedJul 1, 2025

Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer

Janine Kövilein, Adam Sorbie, Sevana Khaloian…·Dirk Haller

This study shows that IBD susceptibility increases the risk of ATF6-driven tumorigenesis in a murine model.

3 citations

mouseexperimental assay

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