Author

John P. Thomson

Cancer Research UKORCID 0000-0002-1630-3159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. Simon HerringtoniD· 2 shared Charlie GourleyiD· 2 shared Clare Bartos· 2 shared Ian Croy· 2 shared Michael ChurchmaniD· 2 shared Robert L. HollisiD· 2 shared Aikou OkamotoiD· 1 shared Ailith EwingiD· 1 shared

Activity by Year

2017-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

C. Simon HerringtonORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 1, 2025

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Ailith Ewing, Alison M. Meynert, Ryan Silk…·Colin A M Semple

The paper identifies two divergent structural variation trajectories in HGSOC that impact patient survival and reveals novel candidate driver genes and mtDNA mutations associated with prognosis.

19 citationstop 3%

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologyGynecologic OncologyPeer-reviewedMay 27, 2025

Combined genomic and molecular analysis defines prognostic markers of relapse in stage IA-IC1 clear cell ovarian carcinoma

Yasushi Iida, Michael Churchman, Robert L. Hollis…·John P. Thomson

This study identifies ARID1A mutation and low CD3+ TIL levels as prognostic markers for relapse in low-stage clear cell ovarian carcinoma.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyWellcome Open ResearchPeer-reviewedAug 22, 2017

Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD

Marcus J. Lyall, Jessy Cartier, James A Richards…·Amanda Jane Drake

This study compares gene expression changes in rodent models of methyl donor deficiency with human NAFLD, finding limited similarity but shared inflammatory and fibrotic pathways.

20 citations

mousebulk RNA-seq

𝕏 PostBluesky