Yuki Tsukada

The paper uses live-imaging to study proliferation dynamics of post-WGD HCT116 cell lineages, finding that multipolar chromosome segregation limits proliferative capacity.

This study shows that mitotic slippage and cytokinesis failure, two mechanisms of whole-genome duplication, differentially affect post-WGD cell viability through distinct chromosome segregation patterns.

The paper simulates cytokinesis by modeling cytoplasmic flow and cortical elasticity interactions, showing spindle-driven flow creates a pressure minimum that initiates cleavage furrow formation.

This study shows that increased neuronal activity in aging C. elegans impairs associative learning behavior, which can be mitigated by dietary changes.

The paper shows that presynaptic MAST kinase in C. elegans controls bidirectional postsynaptic responses to encode thermal stimulus valence through opposing signals.

This paper develops an inverse reinforcement learning framework to identify animal behavioral strategies from time-series data, applied to C. elegans thermotaxis, revealing distinct strategies for fed and starved worms.