Rachel McAllister

This paper describes a protocol for isolating and lipidomic profiling of neuronal lipid droplets, revealing their unique lipid composition and potential role in neurodegenerative disorders.

This paper uses native mass spectrometry to show BTK recruits to membranes via phosphatidylserine and is activated by PIP3, proposing a two-step mechanism for membrane recruitment and activation.

The paper shows that DDHD2 is essential for neurons to use fatty acids from lipid droplets as an energy source during activity when glucose is unavailable.

This paper introduces a platform for high-throughput extraction of membrane proteins into native nanodiscs while preserving their local membrane context and provides a database for optimized extraction conditions.