Author

Steven E. Stayrook

Yale UniversityORCID 0000-0002-1677-8293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Approach:biophysical modeling· 1 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

Christopher K NgiD· 1 shared Daryl E. KleiniD· 1 shared Hengyi LiiD· 1 shared James W. MurphyiD· 1 shared Jeannine M. MendrolaiD· 1 shared Jianan ZhangiD· 1 shared Kathryn M. FergusoniD· 1 shared Mark A. LemmoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Christopher K NgORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 22, 2026

Dual recognition of negative charge by pleckstrin homology (PH) domains

Christopher K Ng, James W. Murphy, Jeannine M. Mendrola…·Mark A. Lemmon

The paper shows PH domains bind both phosphoinositides and negatively charged protein regions, expanding their regulatory roles beyond membrane targeting.

DOI 10.64898/2026.09.21.753330

yeastprotein structure

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedJan 18, 2025

Physical basis for the interaction between Drosophila ROS1 and the GPCR BOSS

Jianan Zhang, Yuko Tsutsui, Hengyi Li…·Daryl E. Klein

This study determines the structure of Drosophila ROS1's extracellular region bound to BOSS, revealing a hydrophobic interaction and beta-strand augmentation mechanism.

4 citations

Drosophilastructural biology

𝕏 PostBluesky