Sefer Elezkurtaj

The paper identifies tumor-reactive TCRs using T/N ratios and validates them with single-cell and spatial data, showing their tumor association and effector phenotype.

This paper introduces a TCR-V(D)J-sequence clustering method to identify tumor-specific common TCRs across cancers, showing their pan-cancer reactivity and potential for therapeutic applications.

This study investigates the role of osteopontin (SPP1/OPN) in colitis-associated carcinoma (CAC) using a multi-omics approach, revealing its indirect immunosuppressive role in the tumor microenvironment.

VoltRon is an R package for spatial omics analysis that integrates multi-resolution and multi-omics data through image registration and spatial alignment.

The paper investigates SARS-CoV-2 entry into the CNS via the olfactory mucosa in COVID-19 patients and demonstrates neurotropism and cerebral thromboembolism.