Author

Anton Dvorzhak

Humboldt-Universität zu BerlinORCID 0000-0002-1787-4850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Dietmar SchmitziD· 3 shared Rosemarie GrantyniD· 2 shared Benjamin R. RostiD· 1 shared Christoph HarmsiD· 1 shared Felicitas BruentgensiD· 1 shared Gisela Lättig-TünnemanniD· 1 shared Jörg BreustedtiD· 1 shared Katalin TörökiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Dietmar SchmitzORCID

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3 papers

Recent·Most cited

NeurosciencePLoS BiologyPeer-reviewedJun 21, 2021

Increased and synchronous recruitment of release sites underlies hippocampal mossy fiber presynaptic potentiation

Marta Orlando, Anton Dvorzhak, Felicitas Bruentgens…·Dietmar Schmitz

The paper investigates presynaptic long-term potentiation in hippocampal mossy fibers, finding increased glutamate release surface area and structural remodeling without changes in calcium channel coupling.

30 citations

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 17, 2020

Expression of a modified astrocytic glutamate transporter alleviates Huntington hypokinesia, promotes synaptic glutamate clearance and counteracts potentially adverse EAAT2 interactions

Stefan Hirschberg, Anton Dvorzhak, Seyed M. A. Rasooli-Nejad…·Rosemarie Grantyn

This study shows that modifying the C-terminal of EAAT2 in a Huntington's disease mouse model reduces hypokinesia symptoms by improving glutamate clearance and reversing some HD-induced changes in EAAT2 interactions.

2 citations

mouseexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedFeb 28, 2019

Single synapse indicators of impaired glutamate clearance derived from fast iGluu imaging of cortical afferents in the striatum of normal and Huntington (Q175) mice

Anton Dvorzhak, Nordine Helassa, Katalin Török…·Rosemarie Grantyn

The paper uses iGluu imaging to analyze glutamate clearance at single synapses in Huntington's disease mice, finding impaired uptake and release in affected synapses.

27 citations

mouseimaging

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