Author

Martin F. Orth

Pathologisches InstitutORCID 0000-0002-1789-6427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Florencia Cidre‐AranaziD· 2 shared Thomas G. P. GrünewaldiD· 2 shared Thomas KirchneriD· 2 shared Ana Sastre· 1 shared Anna C. EhlersiD· 1 shared Annelore Altendorf-Hofmann· 1 shared Aruna MarchettoiD· 1 shared Danny A. ZwijnenburgiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Florencia Cidre‐AranazORCID

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2 papers

Recent·Most cited

GenomicsCell ReportsPeer-reviewedDec 1, 2022

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

Martin F. Orth, Didier Surdez, Tobias Faehling…·Thomas G. P. Grünewald

The paper presents a multi-omics cell line atlas for Ewing sarcoma, identifying new target genes and regulatory mechanisms of EWSR1-ETS fusion oncogenes.

88 citationstop 1%

humanwhole-genome sequencing

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Cancer BiologybioRxivPreprintMar 8, 2019

Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas

Martin F. Orth, Veit L. Buecklein, Eric Kampmann…·Thomas Knösel

This study examines PD-L1 and PD-1 expression in soft tissue sarcomas and finds associations with TILs and poor clinical outcomes, supporting immune checkpoint inhibition in PD-L1-positive cases.

DOI 10.1101/569418

humanbulk RNA-seq

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