BiochemistryJournal of Biological ChemistryPeer-reviewed
Fatty acid oxidation drives hydrogen peroxide production by α-ketoglutarate dehydrogenase
Cathryn Grayson, Ben Faerman, Olivia Koufos, Ryan J. Mailloux
This study identifies α-ketoglutarate dehydrogenase (KGDH) as a major source of mitochondrial hydrogen peroxide (mH2O2) during fatty acid oxidation, showing sex-independent effects.
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