Anh L. Vo

The paper shows that early clonal dominance in B-cell precursors after vaccination predicts the breadth of HIV-neutralizing antibodies in rhesus macaques.

This study shows that a germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques by priming V2-apex bnAb B cell precursors.

The paper designs native-like HIV Env single-chain trimers (SCTs) that are stable, immunogenic, and compatible with vaccine delivery methods.

This study shows that germline-targeting SCIVs can activate and expand B cells expressing V2-apex bnAb-like precursors in rhesus macaques.