Reidun Twarock

This study identifies multiple dispersed packaging signals in the SARS-CoV-2 genome that cooperate to direct RNA packaging into virions, revealing a dynamic mechanism for coronavirus genome assembly.

The paper introduces a geometric criterion to quantify deviations in HIV-1 capsid structure from idealized models and links these deviations to biophysical properties and function.

This study demonstrates how a circularly permuted enzyme can assemble into various hollow structures using pentamers, guided by structural and geometrical principles.

The paper shows that a single point mutation in a virus-like capsid can drive the formation of tetrahedral structures instead of the typical icosahedral symmetry.

The paper uses X-ray footprinting to determine the secondary structures of bacteriophage MS2 RNA in different states, revealing packaging signals and the impact of the Maturation Protein on RNA conformation and capsid structure.