Author
University of OttawaORCID 0000-0002-1873-8500Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Abolfazl Nik-Akhtar, Sophia Vanegas Pineda, Jacob Ouellet…·Shannon A. Bainbridge
This study shows PARP1/2-linked ADP-ribosylation impairs trophoblast mitochondrial respiration in inflammation-mediated preeclampsia, with olaparib improving respiration.
Andrew I. Mikhail, Sean Y. Ng, Magda A. Lesinski…·Vladimir Ljubicic
This study shows that CARM1 activity increases in neuromuscular junction instability and muscle atrophy in mice and humans, correlating with NMJ dysfunction and muscle health decline.
Alessandra Tammaro, Eileen G. Daniels, Iman Man Hu…·Georges E. Janssens
This paper identifies a selective HDAC1/2 inhibitor, Cmpd60, that rejuvenates multiple organ systems in aged mice through transcriptional effects mimicking genetic longevity interventions.
Fahmida Jahan, Goutham Vasam, Yusmaris Cariaco…·Shannon A. Bainbridge
Boosting NAD+ levels prevent inflammatory-driven preeclampsia by improving placental mitochondrial function.