Author

Kristen E. Funk

University of North Carolina at CharlotteORCID 0000-0002-1912-1430Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Katie L. Reagin· 2 shared Aayush Bhatt· 1 shared Autumn E. Tucker· 1 shared Bree Kurtz· 1 shared Britanie M. Blackhurst· 1 shared Emily Kretchmer· 1 shared Jennifer W Weller· 1 shared Katherine A. Jensen· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

Katie L. Reagin

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 17, 2026

CD8⁺ T cells induce interstrand crosslinking-associated DNA damage in neurons

Britanie M. Blackhurst, Aayush Bhatt, Emily Kretchmer…·Kristen E. Funk

This study shows CD8+ T cells induce interstrand crosslinking-like DNA damage in neurons, contributing to neurologic dysfunction in viral infections and neurodegenerative diseases.

DOI 10.64898/2026.03.14.711737

humanbulk RNA-seq

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NeurosciencebioRxivPreprintFeb 16, 2026

RNA-seq variants reveal distinct patterns in the aging epitranscriptome: an in-depth analysis of age-matched Alzheimer's Disease patients and a cognitively normal cohort

Katherine A. Jensen, Jennifer W Weller, Kristen E. Funk

The paper analyzes RNA-seq variants to identify epitranscriptomic differences between Alzheimer's Disease and cognitively normal aged brains, finding 544 hyper-modified genes and 17 differentially modified genes.

DOI 10.64898/2026.02.14.705891

humanbulk RNA-seq

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ImmunologyAging CellPeer-reviewedNov 17, 2024

Antigen non-specific CD8+ T cells accelerate cognitive decline in aged mice following respiratory coronavirus infection

Katie L. Reagin, Rae‐Ling Lee, Luke A. Williams…·Kristen E. Funk

This study shows that aged mice infected with coronavirus have increased brain CD8+ T cells that cause cognitive decline through IFN-gamma secretion.

9 citations

mousebulk RNA-seq

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