Dimphna H. Meijer

This study determines the trimeric structures of FAM171A1 and FAM171A2 extracellular domains, revealing a novel structural superfamily and their oligomerization properties.

The paper shows that a mutation in teneurin-3 disrupts trans adhesion specifically in splice isoforms containing insert A, contributing to microphthalmia.

autoMEA is a machine learning tool for automated burst detection in multi-electrode array data, showing accuracy comparable to manual analysis in detecting network dynamics.

This study shows how alternative splicing of teneurin-3 affects dimer formation and neuronal recognition through structural changes.