Author

Bo Yu

Fred Hutch Cancer CenterORCID 0000-0002-2045-8567Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bo Yu3 papers · National Engineering Research Center for Wheat

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ali ShojaieiD· 1 shared Danwei HuangfuiD· 1 shared Dingyu LiuiD· 1 shared Guanghao QiiD· 1 shared Li HsuiD· 1 shared Marie BleakleyiD· 1 shared Philip H BradleyiD· 1 shared Si LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Ali ShojaieORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 31, 2025

CausalGRN: deciphering causal gene regulatory networks from single-cell CRISPR screens

Bo Yu, Dingyu Liu, Guanghao Qi…·Wei Sun

CausalGRN infers causal gene regulatory networks from single-cell CRISPR screens and predicts responses to unseen perturbations with improved accuracy.

DOI 10.64898/2025.12.30.692369

scRNA-seqstatistical model

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 29, 2025

Characterization of Cancer-Reactive T Cells and Neoantigen-specific T Cell Receptors

Wei Sun, Si Liu, Bo Yu…·Marie Bleakley

The paper develops computational tools to identify cancer-reactive T cells and neoantigen-specific TCRs, showing their variability across cancer types and predictive value for immunotherapy response.

DOI 10.1101/2025.10.29.685473

humanbulk RNA-seq

𝕏 PostBluesky