Katsuyuki Yugi

The paper compares metabolic dysregulation in obese mice during feeding and fasting using multi-omics data, revealing opposite metabolic shifts linked to obesity.

The paper introduces transomics2cytoscape, an R package for automated 2.5D visualization of trans-omics networks, enabling rapid and dynamic interpretation of multi-omics data.

This study uses multiomic analysis of skeletal muscle in obese and healthy mice to reveal differences in metabolic regulation by metabolites and genes after glucose administration.

The paper analyzes trans-omic data from healthy and obese mice to reveal that glucose-responsive liver metabolism is regulated by rapid changes in metabolites and gene expression in the healthy state, and by slow transcriptional regulation in the obese state.

The paper constructs a trans-omic network of insulin action using phosphoproteomic, transcriptomic, and metabolomic data to identify fed and fasting insulin signals.