Sharvari Mankame

DeepSomatic is a deep learning method for detecting somatic variants from short-read and long-read sequencing data, outperforming existing callers, especially for indels.

This study shows that cell-free DNA (cfDNA) can track glioblastoma tumor burden and treatment response over time using in vitro models.

The paper tests if optogenetic stimulation of specific dopamine receptor neurons in the nucleus accumbens reduces cocaine seeking in male rats, finding it reduces seeking when targeting D2DR neurons.