Author
Zehua Zeng
University of Science and Technology BeijingORCID 0000-0002-2109-0418Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author links10 papers
Recent·Most cited
- BioinformaticsbioRxivPreprint
OmicOS: A Comprehensive Omics Ecosystem Infrastructure and Agent System for the AI Era
Zehua Zeng, Xu Meng, LH Hu…·Hongwu Du
OmicOS provides an agent-operable omics ecosystem that enables AI systems to execute and verify analyses using community methods, achieving high performance in benchmark tasks.
1 citation - BioinformaticsbioRxivPreprint
OmicClaw: executable and reproducible natural-language multi-omics analysis over the unified OmicVerse ecosystem.
Zehua Zeng, Xuehai Wang, Zhi Luo…·Hongwei Du
OmicClaw provides a natural-language framework for reproducible multi-omics analysis using the OmicVerse ecosystem, improving performance over baseline models in complex workflows.
- BioinformaticsbioRxivPreprint
PantheonOS: An Evolvable Multi-Agent Framework for Automatic Genomics Discovery
Weize Xu, Erwin Poussi, Quan Zhong…·Xiaojie Qiu
PantheonOS introduces a multi-agent framework for automated genomics analysis, achieving super-human performance in batch correction and gene panel selection across diverse biological tasks.
- BioinformaticsiMetaOmics.Peer-reviewed
CellOntologyMapper: Consensus mapping of cell type annotation
Zehua Zeng, Xuehai Wang, Hongwu Du, Cencan Xing
CellOntologyMapper standardizes cell type annotations by mapping user-defined names to standardized ontological terms, improving data integration and analysis across diverse single-cell datasets.
DOI 10.1002/imo2.70064 - GenomicsbioRxivPreprint
MERFISH+, a large-scale, multi-omics spatial technology resolves the molecular holograms of the 3D human developing heart
Colin Kern, Qingquan Zhang, Yifan Lu…·Bogdan Bintu
MERFISH+ enables high-resolution spatial multi-omics mapping of gene expression and chromatin organization in developing human hearts with subcellular resolution.
9 citations - BioinformaticsbioRxivPreprint
FT-Kernel: An innovative kernel for decoding cellular secrets related time
Cencan Xing, Yuqing Ms, Yanting Wang…·Zehua Zeng
FT-Kernel predicts cell fate factors and dynamics along pseudotime using cell-state density and regression weights, outperforming existing methods in capturing lineage transitions and interactions.
DOI 10.1101/2025.03.01.640966 - BioinformaticsNature CommunicationsPeer-reviewed
OmicVerse: A single pipeline for exploring the entire transcriptome universe
Zehua Zeng, Yuqing Ma, Lei Hu…·Hongwu Du
OmicVerse integrates bulk and single-cell RNA-seq analysis with a pipeline that restores continuity in interrupted single-cell data using Beta-Variational AutoEncoder and graph neural networks.
103 citationstop 1% - BioinformaticsbioRxivPreprint
Identify the origin and end cells and infer the trajectory of cellular fate automatically
Zehua Zeng, Cencan Xing, Lei Hu…·Hongwu Du
This paper introduces scLTNN, a method for automatically inferring origin and end cell states and developmental trajectories from scRNA-seq data with low computational cost.
- BioinformaticsbioRxivPreprint
Predictions for the binding domain and potential new drug targets of 2019-nCoV
Zehua Zeng, Zhi Yong Luo, Hongwu Du
The paper predicts the binding domain and identifies potential new drug targets for 2019-nCoV by analyzing its surface glycoprotein and comparing it to SARS-CoV.
1 citation