Author

Laurent Pessaint

BioqualORCID 0000-0002-2126-3008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:non-human primate· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:imaging· 1

Frequent Co-Authors

Alan DodsoniD· 2 shared Alex Van RyiD· 2 shared Amy R. Henry· 2 shared Anna Mychalowych· 2 shared Anthony CookiD· 2 shared Barbara J. FlynniD· 2 shared Daniel C. DouekiD· 2 shared Dillon R. Flebbe· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Alan DodsonORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 11, 2025

Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines

Amin Addetia, Alexandra Schäfer, Kaitlin R. Sprouse…·David Veesler

This paper designs multivalent RBD nanoparticle vaccines that overcome immune imprinting and provide broad protection against SARS-CoV-2 variants and sarbecoviruses.

4 citations

non-human primateproteomics

𝕏 PostBluesky

ImmunologyNature ImmunologyPeer-reviewedSep 3, 2024

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

Matthew Gagné, Barbara J. Flynn, Shayne F. Andrew…·Robert A. Seder

This study shows that mucosal adenoviral-vectored vaccines provide durable protection against XBB.1.16 infection in nonhuman primates, outperforming intramuscular boosting in reducing virus replication in both upper and lower airways.

78 citationstop 1%

non-human primateexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 22, 2023

Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates

Juan I. Moliva, Shayne F. Andrew, Barbara J. Flynn…·Nancy J. Sullivan

This study shows a gorilla adenovirus-based vaccine provides durable immunity against SARS-CoV-2 in both airways of non-human primates, with enhanced protection from aerosol delivery and prime-boost regimens.

5 citations

non-human primateproteomics

𝕏 PostBluesky