Author

Chao Zheng

Yale UniversityORCID 0000-0002-2179-8096Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chao Zheng1 paper · University ofToronto

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:snRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Zhengxin CaiiD· 2 shared Austin J. StoneriD· 1 shared Daniel HoldeniD· 1 shared Jie TongiD· 1 shared Joshua M. SpurrieriD· 1 shared Krista Fowles· 1 shared Kyle C. Wilcox· 1 shared LaShae NicholsoniD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Zhengxin CaiORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 15, 2023

Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer's Knock-in Mice Require Cellular Prion Protein

Austin J. Stoner, Li Fu, LaShae Nicholson…·Stephen M. Strittmatter

This study shows that PrPC is necessary for synapse loss, phospho-tau accumulation, and neuronal gene expression changes in Alzheimer's knock-in mice, suggesting targeting the Aβo-PrPC interaction could prevent these pathologies.

1 citation

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NeuroscienceEuropean Journal of Nuclear Medicine and Molecular ImagingPeer-reviewedNov 10, 2021

A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: Synthesis and preclinical characterization of SDM-16

Chao Zheng, Daniel Holden, Ming‐Qiang Zheng…·Zhengxin Cai

This paper develops and evaluates [18F]SDM-16, a metabolically stable SV2A PET tracer, showing high affinity and specific binding in nonhuman primate brains.

36 citations

non-human primateimaging

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