Jessica Shiu

The paper develops a pigmented human epidermal equivalent model and shows it has enhanced differentiation potential compared to conventional models.

This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.

This study identifies LNM cells as a pre-malignant state in melanoma initiation, showing they pre-exist in normal skin, expand with Braf activation, and contribute to drug resistance.

This study uses single-cell and spatial transcriptomics to analyze vulvar lichen sclerosus, identifying molecular changes and signaling pathways involved in the disease.

The paper identifies keratinocyte subpopulations in stable vitiligo skin that drive disease persistence through CXCL signaling and altered metabolism.