Nicholaus L. DeCuzzi

This study shows that the eIF4B RRM regulates stress granule assembly and translational repression during oxidative stress.

The paper introduces a far-red FRET biosensor for AMPK activity, enabling multiplexed imaging of single-cell bioenergetic homeostasis and reveals kinetic coupling between AMPK and ATP/ADP ratio.

This paper develops two red-FRET ERK biosensors, REKAR67 and REKAR76, which operate in the 670-720 nm range and are spectrally compatible with existing biosensors for single-cell ERK activity measurement.

The paper shows pro-inflammatory cytokines induce SPREADs in human airway epithelial cells, correlating with barrier dysfunction, and that anti-inflammatory drugs suppress these SPREADs.