Emanuel Soda

This paper shows that extending G1 phase in cancer cells creates a therapeutic window for epigenetic drugs, with LSD1 inhibition and CDK4/6 inhibition working synergistically to induce differentiation and improve survival in AML models.

This study uses 3D diffusion autoencoders to derive latent cardiac MRI phenotypes, finds they share a genetic basis with cardiometabolic traits, and shows predictive power for disease risk.

This paper introduces an automated method for analyzing the cell cycle in both adherent and non-adherent cells using machine learning, validated in AML cell lines and drug response testing.