Wade F. Zeno

This study shows that ionic strength and ionization affect membrane-tethered polymer conformation, which influences membrane curvature generation through changes in brush thickness and grafting density.

This study identifies dimer opening in CK-BB as a mechanism for sensing membrane curvature and regulating ATP regeneration under acidic conditions and substrate binding.

This study shows clathrin alone can drive membrane fission in vitro, with stronger assembly leading to weaker fission, suggesting lattice curvature, not just recruitment, drives membrane remodeling.

This study investigates how membrane phase, charge, and curvature jointly regulate α-synuclein binding dynamics using experimental and simulation methods.

This study shows cholesterol's effect on α-synuclein binding depends on membrane packing state, with cholesterol reducing, enhancing, or having little effect based on lipid composition and curvature.

This study shows that membrane curvature and lipid composition together influence oxidation rates in lipid bilayers, with curvature increasing oxidation and cholesterol modulating this effect.

This study shows that fusing an amphipathic peptide to nanodiscs enhances endocytic uptake and reduces endosomal sequestration, improving drug delivery efficiency.

This study shows graphene quantum dots reduce oxidative stress in E. coli by protecting membranes and intracellular redox balance.

This paper introduces a recombinant protein platform to measure binding affinity of inducible amphipathic helices to membranes using fluorescence anisotropy.

This study shows that α-Synuclein's structured N-terminal domain and disordered C-terminal domain work together to enhance membrane remodeling through synergistic electrostatic and curvature effects.

The paper develops a bilayer continuum model to predict how lipid composition affects protein curvature sensing in membranes.

This study shows that N-terminal acetylation of alpha-synuclein reduces its dependence on anionic lipids for membrane binding, demonstrating that membrane packing defects alone can drive binding.

This study shows clathrin is a strong membrane curvature sensor, with its sensitivity amplified by adaptor proteins, highlighting the role of protein networks in curvature sensing.