Author

Andrew H. Beaven

National Institutes of HealthORCID 0000-0002-3006-3702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:simulation· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander J. SodtiD· 4 shared Amirali HosseiniD· 2 shared Andrew F.X. GoldbergiD· 1 shared Ariel E. MatthewsiD· 1 shared Breyanna Lynn CavanaughiD· 1 shared David H. JohnsoniD· 1 shared Hai LiniD· 1 shared Jefferson D. KnightiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiophysics

Alexander J. SodtORCID

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4 papers

Recent·Most cited

NeuroscienceJournal of Biological ChemistryPeer-reviewedMay 12, 2026

Photoreceptor outer segment disk rim curvature relies on a tetraspanin interaction web

Rudrick C. Boucher, Michelle L. Milstein, Amirali Hossein…·Andrew F.X. Goldberg

This study investigates the structural role of PRPH2 and Rom1 in photoreceptor outer segment disk curvature using BN-PAGE and MD simulations, revealing their interaction web and curvature mechanisms.

DOI 10.1016/j.jbc.2026.113136

experimental assaysimulation

𝕏 PostBluesky

BiophysicsBiophysical JournalPeer-reviewedJan 6, 2026

Predicting protein curvature sensing across membrane compositions with a bilayer continuum model

Yiben Fu, David H. Johnson, Andrew H. Beaven…·Margaret E. Johnson

The paper develops a bilayer continuum model to predict how lipid composition affects protein curvature sensing in membranes.

3 citations

deep learningstatistical model

𝕏 PostBluesky

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedJun 18, 2024

Softening in two-component lipid mixtures by spontaneous curvature variance

Amirali Hossein, Andrew H. Beaven, Kayla C. Sapp, Alexander J. Sodt

This study shows that variance in curvature sensitivity of lipids affects membrane stiffness, with coarse-grained models showing greater softening due to clustering.

17 citations

statistical modelsimulation

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BiophysicsbioRxivPreprintJan 10, 2024

Synaptotagmin 7 C2 domains induce membrane curvature stress via electrostatic interactions and the wedge mechanism

Andrew H. Beaven, Vrishank Bikkumalla, Nara L. Chon…·Alexander J. Sodt

This study investigates how Syt-7 C2 domains generate membrane curvature through electrostatic interactions and the wedge mechanism, using simulations and assays.

1 citation

proteomicsbiophysical modeling

𝕏 PostBluesky