Taylor Wintler

The paper analyzes RNA-seq data from sleep-deprived and recovery sleep mice to identify gene expression changes linked to sleep homeostasis and SD effects.

This study shows that Shank3{Delta}C mice have reduced total sleep, altered REM/NREM sleep dynamics, and impaired sleep latency responses, suggesting sleep abnormalities are a core feature of ASD.

This study shows that Shank3 modulates sleep and circadian transcription factor expression in mice, with sleep deprivation exacerbating gene expression differences between Shank3 mutants and wild types.