Yuan Lü

The paper identifies a recessive oca2 mutation causing albinism in Xiphophorus hellerii fish and explores its role in pigment biology and melanoma.

The paper investigates how hybridization affects gene expression in brain tissues by identifying cell type-specific regulatory variation in interspecies fish hybrids.

This study examines the transcriptional response of Pseudogymnoascus destructans to copper stress, identifying differentially expressed genes and potential virulence factors under varying copper conditions.

The paper tests the function of adgre5 alleles in melanoma development using Xiphophorus hybrids and finds that the X. birchmanni allele suppresses melanoma while the X. malinche allele does not.

The paper identifies a locus in one Xiphophorus species that represses an oncogene from another species, providing insights into hybrid incompatibility and pigment cell regulation.

The paper provides complete genomes for all 26 Xiphophorus species, resolves conflicting phylogeny, and shows hybridization precedes speciation in this genus.

The paper compares transcriptional profiles of two tumor types in a transgenic medaka model to identify how transcriptomic backgrounds influence oncogenic outcomes.