MicrobiologyProceedings of the National Academy of SciencesPeer-reviewed
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus
Mehmet Hakan Guney, Karthika Nagalekshmi, Sean Matthew McCauley…·Jeremy Luban
This study identifies IFIH1 (MDA5) as essential for innate immune detection of intron-containing RNA from the HIV-1 provirus, linking it to chronic inflammation in HIV-1 patients.
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