Author

Sean Matthew McCauley

University of Massachusetts Chan Medical SchoolORCID 0000-0002-7616-7902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jeremy LubaniD· 2 shared Mehmet Hakan GuneyiD· 2 shared Ann DauphiniD· 1 shared Claudia CarboneiD· 1 shared Karthika NagalekshmiiD· 1 shared Kyusik KimiD· 1 shared Leonid YurkovetskiyiD· 1 shared Ozkan Aydemir· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Jeremy LubanORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 17, 2023

IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus

Mehmet Hakan Guney, Karthika Nagalekshmi, Sean Matthew McCauley…·Jeremy Luban

This study identifies IFIH1 (MDA5) as essential for innate immune detection of intron-containing RNA from the HIV-1 provirus, linking it to chronic inflammation in HIV-1 patients.

DOI 10.1101/2023.11.17.567619

humanbulk RNA-seq

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Molecular BiologyNature MicrobiologyPeer-reviewedSep 28, 2018

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

Leonid Yurkovetskiy, Mehmet Hakan Guney, Kyusik Kim…·Jeremy Luban

This study identifies Vpx and Vpr as viral proteins that counteract the HUSH complex to activate provirus transcription in primate immunodeficiency viruses.

143 citationstop 2%

humanexperimental assay

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